Baseline correction/z scoring for signed MNE stc data

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Dear MNE users,

I would like to compute some statistics on different conditions using the
Spatio-temporal clustering method implemented in MNE. I would like to use
the signed MNE values as STC data. I was thinking, if I need to do any sort
of normalization (i.e., a baseline correction or z scoring over the
conditions) before doing the statistics. Any feedback would be helpful.

Thanks and best,
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hi Dip,

sorry for the late reply.

If STC contains signed values they should be zero mean during baseline so
no centering should be needed. Regarding scaling it depends on the stat
you use. If you use a t-test it estimates the standard deviation so apply
a scaling factor should not have any effect of the T-stats.