# BEM construction - FLAIR vs FLASH?

**URL:** https://mne.discourse.group/t/bem-construction-flair-vs-flash/678
**Category:** Mailing List Archive (read-only)
**Tags:** list-archive
**Created:** [February 28, 2014, 1:40am UTC](https://mne.discourse.group/t/bem-construction-flair-vs-flash/678 "2014-02-28T01:40:25Z")
**Posts on this page:** 5
**Page:** 1

<div class="post-metadata">

### Author: ![system](https://global.discourse-cdn.com/free1/uploads/mne/original/1X/85cc6bd2b69cb698a166dc6d880fb550510d0144.jpeg) [@system](https://mne.discourse.group/u/system)
#### Post date: [February 28, 2014, 1:40am UTC](https://mne.discourse.group/t/bem-construction-flair-vs-flash/678/1 "2014-02-28T01:40:25Z")

</div>

For BEM construction, can MNE take advantage of Freesurfer's multispectral  
imaging pipeline (using a single FLAIR scan), or is it still better to  
collect the two FLASH scans? I grepped through the linux & python scripts  
but didn't see anything promising. Cutting a scan would free up some MRI  
time on a new project, but I don't want to hamstring myself.

Thanks,

Jon  
-------------- next part --------------  
An HTML attachment was scrubbed...  
URL: [http://mail.nmr.mgh.harvard.edu/pipermail/mne\_analysis/attachments/20140227/62d676e0/attachment.html](http://mail.nmr.mgh.harvard.edu/pipermail/mne_analysis/attachments/20140227/62d676e0/attachment.html)

---

<div class="post-metadata">

### Author: ![system](https://global.discourse-cdn.com/free1/uploads/mne/original/1X/85cc6bd2b69cb698a166dc6d880fb550510d0144.jpeg) [@system](https://mne.discourse.group/u/system)
#### Post date: [February 28, 2014, 12:36pm UTC](https://mne.discourse.group/t/bem-construction-flair-vs-flash/678/2 "2014-02-28T12:36:55Z")

</div>

hi Jon,

> For BEM construction, can MNE take advantage of Freesurfer's multispectral  
> imaging pipeline (using a single FLAIR scan), or is it still better to  
> collect the two FLASH scans? I grepped through the linux & python scripts  
> but didn't see anything promising. Cutting a scan would free up some MRI  
> time on a new project, but I don't want to hamstring myself.

I am not aware of a solution using FLAIR. I guess it could work should you  
dig deep enough in the mne\_flash\_bem shell script.

Let us know if you find a way. That would be a nice contribution for MNE users.

Best,  
Alex

---

<div class="post-metadata">

### Author: ![system](https://global.discourse-cdn.com/free1/uploads/mne/original/1X/85cc6bd2b69cb698a166dc6d880fb550510d0144.jpeg) [@system](https://mne.discourse.group/u/system)
#### Post date: [February 28, 2014, 2:35pm UTC](https://mne.discourse.group/t/bem-construction-flair-vs-flash/678/3 "2014-02-28T14:35:30Z")

</div>

Given the contrast in FLAIR images IMO it would not be possible to  
use the standard mne\_flash\_bem script tools to generate useful bem  
surfaces (you could obviously write your own). I can help you out by  
saying that in my experience, you can get away with only utilizing the  
FLASH 5 data (although this assumes you have similar image quality).  
If you are getting very good contrast between the critical tissues, in  
your FLASH 5 alone. This should save you half the time.

D

---

<div class="post-metadata">

### Author: ![system](https://global.discourse-cdn.com/free1/uploads/mne/original/1X/85cc6bd2b69cb698a166dc6d880fb550510d0144.jpeg) [@system](https://mne.discourse.group/u/system)
#### Post date: [February 28, 2014, 3:20pm UTC](https://mne.discourse.group/t/bem-construction-flair-vs-flash/678/4 "2014-02-28T15:20:06Z")

</div>

Dear Dan, Jon and Alex,

Having recently received the sequence parameters from Alex (thx!) for the multi-echo FLASH, I can second Dan's observation of practically identical surfaces using 5 deg alone vs. 5 and 30 degs. This is on a 3T Skyra, anyone care to weigh in with experiences from other scanners?

My naive take on FLAIR is that it might help getting the pia-dura separation right, i.e., improve cortex thickness estimates, but probably not that critical for M/EEG forward models?

/Chris  
/CFIN, Aarhus, Denmark

---

<div class="post-metadata">

### Author: ![system](https://global.discourse-cdn.com/free1/uploads/mne/original/1X/85cc6bd2b69cb698a166dc6d880fb550510d0144.jpeg) [@system](https://mne.discourse.group/u/system)
#### Post date: [February 28, 2014, 3:53pm UTC](https://mne.discourse.group/t/bem-construction-flair-vs-flash/678/5 "2014-02-28T15:53:07Z")

</div>

To speak to the second point. In MNE the pial surface is not used in  
the forward model. Furthermore, I would expect (read I have no direct  
tests) that you would get more benefit (relative to effort) from  
correctly measuring the inner skull boundary then from adding in  
another layer for the pial surface. And FLAIR (Fluid Attenuation  
Inversion Recovery) will unfortunately not help you with that  
measurement, due to its intentional insensitivity to CSF (hence being  
beneficial for pial measurements). However, for cortical thickness  
measurements, this is supposed to be very useful.

D
